Systematic Evaluation of Candidate Blood Markers for Detecting Ovarian Cancer
نویسندگان
چکیده
منابع مشابه
Systematic Evaluation of Candidate Blood Markers for Detecting Ovarian Cancer
BACKGROUND Epithelial ovarian cancer is a significant cause of mortality both in the United States and worldwide, due largely to the high proportion of cases that present at a late stage, when survival is extremely poor. Early detection of epithelial ovarian cancer, and of the serous subtype in particular, is a promising strategy for saving lives. The low prevalence of ovarian cancer makes the ...
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Kathryn L. Terrya, Patrick M. Slussb, Steven J. Skatesc,d, Samuel C. Mokd, Bin Yed, Allison F. Vitonisa and Daniel W. Cramera Ob-Gyn Center Epidemiology Center, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women’s Hospital, Boston, MA, USA Reproductive Endocrinology Unit Laboratory, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA Biostatist...
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BACKGROUND Evaluating diagnostic and early detection biomarkers requires comparing serum protein concentrations among biosamples ascertained from subjects with and without cancer. Efforts are generally made to standardize blood processing and storage conditions for cases and controls, but blood sample collection conditions cannot be completely controlled. For example, blood samples from cases a...
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Ovarian cancer remains a deadly threat to women as the disease is often diagnosed in the late stages when the chance of survival is low. There are no good biomarkers available for early detection and only a few markers have shown clinical utility for prognosis, response to therapy and disease recurrence. We mined conditioned media of four ovarian cancer cell lines (HTB75, TOV-112D, TOV-21G and ...
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Reply Dr Qureshi’s interest in our article is most welcome. The results of the audit from Dr Qureshi’s unit suggest that the introduction of a standardised proforma might be expected to improve compliance with RCOG guideline recommendations. As regards to whether the procedure is called ‘laparoscopic tubal occlusion’ or ‘laparoscopic sterilisation’, whilst the former may be more precise, the la...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2008
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0002633